Epicore Biosystems Secures Additional $6M for Sweat-Sensing Wearable Expansion

What You Should Know: 

– Epicore Biosystems, a leader in digital health solutions specializing in advanced sweat-sensing wearables, today announced an additional $6M in Series B funding. 

– The funding brings the company’s total Series B raise to $32M and includes backing from a new San Francisco-based investor and notable angel investors, alongside continued support from existing investors Alumni Ventures and Joyance Partners.

This follow-on investment builds upon Epicore’s initial $26M Series B round led by the Steele Foundation for Hope. The combined capital infusion positions the company to significantly accelerate its global expansion efforts and scale its next-generation sweat-sensing technologies.

Advancing Sweat-Sensing Technology

Epicore Biosystems develops sophisticated wearables that non-invasively measure sweat composition and fluid losses in real-time. These devices also track key physiological markers such as skin temperature, motion, and thermal flux to detect early indicators of fatigue, heat exhaustion, and performance levels.

The company’s flagship product, Connected Hydration, exemplifies this technology. It’s the first smart wearable solution capable of capturing novel hydration data streams and delivering immediate haptic alerts to guide users through personalized hydration routines. This proactive approach helps wearers manage cognitive and physical recovery needs effectively. The impact and utility of Connected Hydration have been documented for industrial workers and athletes, including a recent publication in Nature Digital Medicine and pilots at major events like the 2025 Super Bowl.

“Connected Hydration seamlessly captures multiple sweat and physiology biomarkers, and provides real-time haptic feedback, allowing the wearer to manage their hydration, fatigue, and recovery needs,” said Dr. Roozbeh Ghaffari, CEO and co-founder of Epicore Biosystems. “We’re thrilled to have mission-driven investors onboard who recognize both the value of new data streams and the utility of biosensor technologies to transform safety, well-being and productivity.”

Diverse Applications and Product Portfolio

Epicore’s suite of sweat-sensing solutions caters to a range of needs. Beyond Connected Hydration tailored for industrial workers, the portfolio includes the Gx Sweat Patch®, commercialized with PepsiCo and Gatorade for athlete hydration management, and the Discovery Patch® Sweat Collection System, an FDA Class I registered device used in clinical trials. These products offer both real-time monitoring and point measurements for physically demanding occupations and wellness applications.

Fueling Global Expansion and Innovation

With the fresh capital, Epicore Biosystems plans to pursue several key growth initiatives:

• Geographic Expansion: Extending the reach of its Connected Hydration solution into industrial markets across Australia, the Middle East, and Asia.
• Scaling Analytics: Enhancing its real-time cloud analytics platform to provide more sophisticated personalized hydration guidance and recommendations.
• New Biomarker Validation: Researching and validating novel sweat biomarkers for potential applications in areas beyond hydration, including kidney health and stress management.

Market Traction

Epicore has established a robust network of enterprise and government partners, demonstrating significant market traction. Collaborators include major corporations like Chevron, PepsiCo, Gatorade, United Airlines, Bechtel, Denka, and Nitto, as well as U.S. military branches like the Air Force, Office of Naval Research, and Army. The company’s solutions are actively deployed across diverse sectors including energy, construction, manufacturing, aviation, and shipping.