Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09162-0Lipoprotein uptake dependent on sulfated glycosaminoglycans linked to cell-surface proteoglycans is a key determinant of ferroptosis sensitivity in cancer.

Jun 11, 2025 - 17:06
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Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09162-0Lipoprotein uptake dependent on sulfated glycosaminoglycans linked to cell-surface proteoglycans is a key determinant of ferroptosis sensitivity in cancer.