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SP140–RESIST pathway regulates interferon mRNA stability and antiviral immunity

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09152-2The antiviral protein SP140 negatively regulates Ifnb1 mRNA stability by directly repressing the expression of the immune regulator RESIST.

Jun 11, 2025 - 17:06
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SP140–RESIST pathway regulates interferon mRNA stability and antiviral immunity

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09152-2The antiviral protein SP140 negatively regulates Ifnb1 mRNA stability by directly repressing the expression of the immune regulator RESIST.

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