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Metabolic adaptations direct cell fate during tissue regeneration
Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09097-6Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment and offering insights for targeted regenerative therapies.
Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09097-6Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment and offering insights for targeted regenerative therapies.
