Yeast produces human DNase1 for the first time

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, among other things, to treat cystic fibrosis. However, it takes considerable effort to produce it in immortalized hamster cells. This process is also costly. It would be far more cost-effective to produce it with undemanding yeast cells.

May 28, 2025 - 17:22
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The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, among other things, to treat cystic fibrosis. However, it takes considerable effort to produce it in immortalized hamster cells. This process is also costly. It would be far more cost-effective to produce it with undemanding yeast cells.