Photo-switchable DNA condensates enable remote-controlled microflow systems

Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists from the Institute of Science Tokyo, Japan. By switching between ultraviolet light (UV) and visible light irradiation, the researchers demonstrated that the novel DNA motifs containing azobenzene can dissociate or reassemble. Furthermore, localized photo-switching within a DNA liquid condensate generated two distinct directional motions. This study can fuel the development of innovative fluid-based diagnostic chips and molecular computers.

Jun 23, 2025 - 19:48
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Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists from the Institute of Science Tokyo, Japan. By switching between ultraviolet light (UV) and visible light irradiation, the researchers demonstrated that the novel DNA motifs containing azobenzene can dissociate or reassemble. Furthermore, localized photo-switching within a DNA liquid condensate generated two distinct directional motions. This study can fuel the development of innovative fluid-based diagnostic chips and molecular computers.