Massively parallel profiling reveals thousands of hidden viral proteins and conserved mechanisms

Scientists at the Broad Institute of MIT and Harvard have identified 4,208 previously unannotated open reading frames (ORFs) across 679 human-associated viral genomes using a high-throughput method called massively parallel ribosome profiling (MPRP).

Jun 17, 2025 - 12:08
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Scientists at the Broad Institute of MIT and Harvard have identified 4,208 previously unannotated open reading frames (ORFs) across 679 human-associated viral genomes using a high-throughput method called massively parallel ribosome profiling (MPRP).