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Detailed molecular steps of blood clotting revealed in new study
Blood clotting is a complex, tightly regulated process involving numerous molecular steps and myriad biomolecules to carry them out, including vitamin K. While the medical field has capitalized on this knowledge to produce medications that toggle up or down vitamin K—to boost or reduce clotting, respectively—scientists had not understood how the integral membrane enzyme utilizing vitamin K, vitamin K-dependent gamma carboxylase (VKGC), manages these activities.
Blood clotting is a complex, tightly regulated process involving numerous molecular steps and myriad biomolecules to carry them out, including vitamin K. While the medical field has capitalized on this knowledge to produce medications that toggle up or down vitamin K—to boost or reduce clotting, respectively—scientists had not understood how the integral membrane enzyme utilizing vitamin K, vitamin K-dependent gamma carboxylase (VKGC), manages these activities.
