Cross-tissue multicellular coordination and its rewiring in cancer
Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09053-4Comprehensive single-cell transcriptomic analysis of 35 human tissues reveals 12 cross-tissue coordinated cellular modules that exhibit intramodule communication and dynamic changes with ageing, and whose organization is perturbed during cancer progression.

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09053-4Comprehensive single-cell transcriptomic analysis of 35 human tissues reveals 12 cross-tissue coordinated cellular modules that exhibit intramodule communication and dynamic changes with ageing, and whose organization is perturbed during cancer progression.