Cross-tissue multicellular coordination and its rewiring in cancer

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09053-4Comprehensive single-cell transcriptomic analysis of 35 human tissues reveals 12 cross-tissue coordinated cellular modules that exhibit intramodule communication and dynamic changes with ageing, and whose organization is perturbed during cancer progression.

May 28, 2025 - 16:40
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Cross-tissue multicellular coordination and its rewiring in cancer

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09053-4Comprehensive single-cell transcriptomic analysis of 35 human tissues reveals 12 cross-tissue coordinated cellular modules that exhibit intramodule communication and dynamic changes with ageing, and whose organization is perturbed during cancer progression.