Translational genomics of osteoarthritis in 1,962,069 individuals

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08771-zA genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of multiple effector genes; 10% of these genes express the target of approved drugs.

Apr 9, 2025 - 16:39
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Translational genomics of osteoarthritis in 1,962,069 individuals

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08771-zA genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of multiple effector genes; 10% of these genes express the target of approved drugs.