Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08917-zA study of human and mouse models of pancreatic cancer finds that inhibiting the lipid kinase PIKfyve interferes with the cancer’s lipid homeostasis, making it a potential target for drug development.

Apr 23, 2025 - 16:18
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Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

Nature, Published online: 23 April 2025; doi:10.1038/s41586-025-08917-zA study of human and mouse models of pancreatic cancer finds that inhibiting the lipid kinase PIKfyve interferes with the cancer’s lipid homeostasis, making it a potential target for drug development.