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Structural insights into human Pol III transcription initiation in action

Nature, Published online: 04 June 2025; doi:10.1038/s41586-025-09093-wReconstitution of seven human RNA polymerase III (Pol III) transcribing complexes (TC4/5/6/8/10/12/13) halted on U6 promoters with nascent RNAs of 4–13 nucleotides offers molecular insights into Pol III dynamics.

Jun 4, 2025 - 16:20
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Structural insights into human Pol III transcription initiation in action

Nature, Published online: 04 June 2025; doi:10.1038/s41586-025-09093-wReconstitution of seven human RNA polymerase III (Pol III) transcribing complexes (TC4/5/6/8/10/12/13) halted on U6 promoters with nascent RNAs of 4–13 nucleotides offers molecular insights into Pol III dynamics.

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