Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis | Science

Chromatin remodelers utilize the energy of adenosine triphosphate (ATP) hydrolysis to slide nucleosomes, regulating chromatin structure and gene activity in cells. In this work, we report structures of imitation switch (ISWI) bound to the nucleosome ...

Jun 5, 2025 - 19:12
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Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis | Science
Chromatin remodelers utilize the energy of adenosine triphosphate (ATP) hydrolysis to slide nucleosomes, regulating chromatin structure and gene activity in cells. In this work, we report structures of imitation switch (ISWI) bound to the nucleosome ...