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Small molecules restore mutant mitochondrial DNA polymerase activity
Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08856-9An activator of DNA polymerase γ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.
Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08856-9An activator of DNA polymerase γ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.
