Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08945-9Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in fibrotic hearts.
Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08945-9Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in fibrotic hearts.
