Preoptic EP3R neurons constitute a two-way switch for fever and torpor

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09056-1Neurons in the median preoptic nucleus that express the prostaglandin EP3 receptor produce prolonged hypothermic responses or hyperthermic responses, respectively, following brief activation or inhibition.

May 28, 2025 - 16:40
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Preoptic EP3R neurons constitute a two-way switch for fever and torpor

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09056-1Neurons in the median preoptic nucleus that express the prostaglandin EP3 receptor produce prolonged hypothermic responses or hyperthermic responses, respectively, following brief activation or inhibition.