Oncogenic fusions converge on shared mechanisms in initiating astroblastoma
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-08981-5The molecular mechanisms of astroblastoma development are identified, whereby distinct gene fusions upregulate shared transcriptional networks to disrupt the normal development of ventral telencephalon neural progenitors, which leads to oncogenesis.
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-08981-5The molecular mechanisms of astroblastoma development are identified, whereby distinct gene fusions upregulate shared transcriptional networks to disrupt the normal development of ventral telencephalon neural progenitors, which leads to oncogenesis.
