Genomes from a four-generation family reveal the rate of new mutations
Nature, Published online: 14 May 2025; doi:10.1038/d41586-025-01474-5The rate at which mutations arise can be estimated by studying multigenerational human families. Reference genomes have been assembled for 28 people from four generations of the same family. This publicly available resource provides insight into the mechanisms that underlie mutations in the most complex regions of the genome.
Nature, Published online: 14 May 2025; doi:10.1038/d41586-025-01474-5The rate at which mutations arise can be estimated by studying multigenerational human families. Reference genomes have been assembled for 28 people from four generations of the same family. This publicly available resource provides insight into the mechanisms that underlie mutations in the most complex regions of the genome.
