Nutrient-driven histone code determines exhausted CD8+ T cell fates | Science

Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on epigenetic modifications that control TEX differentiation ...

Feb 9, 2025 - 21:53
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Nutrient-driven histone code determines exhausted CD8+ T cell fates | Science
Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on epigenetic modifications that control TEX differentiation ...