Multi-interface licensing of protein import into a phage nucleus
Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08547-xThis study uncovers a highly conserved jumbo phage protein, Imp1, that possesses multiple interfaces to license protein import into a proteinaceous nucleus-like compartment, using a genetic selection that forces the phage to decrease or abolish the import of specific proteins.
![Multi-interface licensing of protein import into a phage nucleus](https://media.springernature.com/m685/springer-static/image/art:10.1038%2Fs41586-024-08547-x/MediaObjects/41586_2024_8547_Fig1_HTML.png)
Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08547-xThis study uncovers a highly conserved jumbo phage protein, Imp1, that possesses multiple interfaces to license protein import into a proteinaceous nucleus-like compartment, using a genetic selection that forces the phage to decrease or abolish the import of specific proteins.