Manipulating DNA repair proteins to improve gene editing outcomes

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was created using a form of gene editing called base editing—a method created by Alexis Komor when she was a postdoctoral scholar in molecular biologist David Liu's group at Harvard University.

Jun 4, 2025 - 15:32
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You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was created using a form of gene editing called base editing—a method created by Alexis Komor when she was a postdoctoral scholar in molecular biologist David Liu's group at Harvard University.