Exogenous RNA surveillance by proton-sensing TRIM25 | Science

Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens with in vitro–transcribed mRNAs in lipid ...

Apr 3, 2025 - 19:11
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Exogenous RNA surveillance by proton-sensing TRIM25 | Science
Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens with in vitro–transcribed mRNAs in lipid ...