Does a cell’s gene expression always reflect its function?

Nature, Published online: 12 February 2025; doi:10.1038/d41586-025-00088-1Defining a cell’s ‘type’ by the RNA transcripts it expresses is popular in biological research, but evidence from zebrafish neurons suggests that transcriptionally similar cells can be functionally diverse.

Feb 12, 2025 - 17:42
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Does a cell’s gene expression always reflect its function?

Nature, Published online: 12 February 2025; doi:10.1038/d41586-025-00088-1Defining a cell’s ‘type’ by the RNA transcripts it expresses is popular in biological research, but evidence from zebrafish neurons suggests that transcriptionally similar cells can be functionally diverse.