CoQ imbalance drives reverse electron transport to disrupt liver metabolism

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09072-1Reverse electron transport is the mechanism behind excess mitochondrial reactive oxygen species in the livers of obese mice, which has implications for developing therapeutics for fatty liver disease in humans.

May 28, 2025 - 16:40
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CoQ imbalance drives reverse electron transport to disrupt liver metabolism

Nature, Published online: 28 May 2025; doi:10.1038/s41586-025-09072-1Reverse electron transport is the mechanism behind excess mitochondrial reactive oxygen species in the livers of obese mice, which has implications for developing therapeutics for fatty liver disease in humans.