Copper death-inhibiting compounds isolated from eucalyptus fruits show promise for cancer therapy
Researchers have isolated two novel bis-β-triketone hybrids, Corymbinols A (1) and B (2a/2b), from the fruits of Corymbia citriodora. Corymbinol A demonstrated a 31% inhibition of cuproptosis in HepG2 cells at a concentration of 20 μM, suggesting its potential as a non-toxic therapeutic option against liver cancer.
Researchers have isolated two novel bis-β-triketone hybrids, Corymbinols A (1) and B (2a/2b), from the fruits of Corymbia citriodora. Corymbinol A demonstrated a 31% inhibition of cuproptosis in HepG2 cells at a concentration of 20 μM, suggesting its potential as a non-toxic therapeutic option against liver cancer.
