Chemists develop new method to synthesize chiral bridged polycyclic compounds for drug discovery

A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II [5 + 2] cycloaddition method to address the challenges of synthesizing chiral bridged polycyclic structures, particularly those with a bridged seven-membered subunit.

Jun 4, 2025 - 18:02
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A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II [5 + 2] cycloaddition method to address the challenges of synthesizing chiral bridged polycyclic structures, particularly those with a bridged seven-membered subunit.