A human-specific enhancer fine-tunes radial glia potency and corticogenesis
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-09002-1HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence between cortical regions through amplified WNT signalling.
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-09002-1HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence between cortical regions through amplified WNT signalling.
