A biotech company says it has bred three pups with traits of the extinct dire wolf

Colossal Biosciences says it used novel gene-editing technology to alter gray wolf DNA to breed the animals. Dire wolves recently featured prominently in the HBO series Game of Thrones.

Apr 8, 2025 - 18:04
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A biotech company says it has bred three pups with traits of the extinct dire wolf
Romulus and Remus, the pups with dire wolf traits that were bred by Colossal Biosciences, are pictured at three months old.

Colossal Biosciences says it used novel gene-editing technology to alter gray wolf DNA to breed the animals. Dire wolves recently featured prominently in the HBO series Game of Thrones.