Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy
Nature, Published online: 12 February 2025; doi:10.1038/s41586-024-08539-xTranscriptional adaptation upregulates UTRN in Duchenne muscular dystrophy (DMD) patients, as supported by several lines of evidence, including the use of splice-switching antisense oligonucleotides to induce the skipping of out-of-frame exons of the DMD gene.
Nature, Published online: 12 February 2025; doi:10.1038/s41586-024-08539-xTranscriptional adaptation upregulates UTRN in Duchenne muscular dystrophy (DMD) patients, as supported by several lines of evidence, including the use of splice-switching antisense oligonucleotides to induce the skipping of out-of-frame exons of the DMD gene.
