Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection | Science

During infections, CD4+ Foxp3+ regulatory T (Treg) cells must control autoreactive CD4+ conventional T (Tconv) cell responses against self-peptide antigens while permitting those against pathogen-derived “nonself” peptides. We defined the basis of this ...

Mar 20, 2025 - 19:12
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Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection | Science
During infections, CD4+ Foxp3+ regulatory T (Treg) cells must control autoreactive CD4+ conventional T (Tconv) cell responses against self-peptide antigens while permitting those against pathogen-derived “nonself” peptides. We defined the basis of this ...