Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00303-zCellular organelles called mitochondria contain DNA and can fuse together or split apart. It emerges that excess fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA.

Feb 19, 2025 - 17:20
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Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00303-zCellular organelles called mitochondria contain DNA and can fuse together or split apart. It emerges that excess fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA.