Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide
Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08683-yComputational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin 4 receptor.
Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08683-yComputational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin 4 receptor.
