Programs, origins and immunomodulatory functions of myeloid cells in glioma

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08633-8A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell types, driven by microenvironmental cues and predictive of therapeutic response.

Feb 26, 2025 - 18:01
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Programs, origins and immunomodulatory functions of myeloid cells in glioma

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08633-8A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell types, driven by microenvironmental cues and predictive of therapeutic response.