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Mechanism for local attenuation of DNA replication at double-strand breaks

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08557-9DNA double-strand breaks induce local genome maintenance and inhibition of replication initiation at nearby topologically associating domains without affecting global DNA synthesis.

Feb 19, 2025 - 17:16
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Mechanism for local attenuation of DNA replication at double-strand breaks

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08557-9DNA double-strand breaks induce local genome maintenance and inhibition of replication initiation at nearby topologically associating domains without affecting global DNA synthesis.

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