Low overlap of transcription factor DNA binding and regulatory targets

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08916-0A near-complete survey of transcription factor activities in Saccharomyces cerevisiae reveals that most transcription factors have both activator and repressor activities and limited overlap between their binding sites on DNA and regulation of nearby genes.

Apr 16, 2025 - 17:15
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Low overlap of transcription factor DNA binding and regulatory targets

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08916-0A near-complete survey of transcription factor activities in Saccharomyces cerevisiae reveals that most transcription factors have both activator and repressor activities and limited overlap between their binding sites on DNA and regulation of nearby genes.