In vitro reconstitution of meiotic DNA double-strand-break formation
Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08551-1The in vitro characterization of a key event in the early stages of meiosis—the induction of double-strand DNA breaks by the SPO11–TOP6BL complex—provides insight into the catalytic mechanism and evolution of SPO11.
Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08551-1The in vitro characterization of a key event in the early stages of meiosis—the induction of double-strand DNA breaks by the SPO11–TOP6BL complex—provides insight into the catalytic mechanism and evolution of SPO11.
