Human-correlated genetic models identify precision therapy for liver cancer
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08585-zAs proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which acts in a highly effective subtype-specific manner in combination with standard-of-care therapy.
Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08585-zAs proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which acts in a highly effective subtype-specific manner in combination with standard-of-care therapy.
