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Genome-coverage single-cell histone modifications for embryo lineage tracing

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08656-1Two new methods, target chromatin indexing and tagmentation (TACIT) and combined TACIT (CoTACIT), enabled single-cell profiling of the epigenome and lineage tracing from mouse zygotes to blastocysts.

Feb 26, 2025 - 17:57
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Genome-coverage single-cell histone modifications for embryo lineage tracing

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08656-1Two new methods, target chromatin indexing and tagmentation (TACIT) and combined TACIT (CoTACIT), enabled single-cell profiling of the epigenome and lineage tracing from mouse zygotes to blastocysts.

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