Extensive mutual influences of SMC complexes shape 3D genome folding

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08638-3Orthogonal acute inducible degradation cell lines are used to delineate the mechanisms of how extrusive cohesin, cohesive cohesin and condensin interact to remodel chromosome architecture from interphase to mitosis.

Feb 26, 2025 - 17:59
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Extensive mutual influences of SMC complexes shape 3D genome folding

Nature, Published online: 26 February 2025; doi:10.1038/s41586-025-08638-3Orthogonal acute inducible degradation cell lines are used to delineate the mechanisms of how extrusive cohesin, cohesive cohesin and condensin interact to remodel chromosome architecture from interphase to mitosis.