Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson's disease protein
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are bound for secretion harbor an N-terminal signal peptide that guides their movement from the endoplasmic reticulum (ER) and Golgi apparatus to the exterior of the cell.
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are bound for secretion harbor an N-terminal signal peptide that guides their movement from the endoplasmic reticulum (ER) and Golgi apparatus to the exterior of the cell.
