.jpg?#)
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08651-6JNJ-9676—a small-molecule inhibitor targeting coronavirus M protein that shows excellent efficacy in Syrian golden hamster models—binds to and stabilizes the M protein dimer in an altered conformational state between its long and short forms, preventing the release of infectious virus.
Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08651-6JNJ-9676—a small-molecule inhibitor targeting coronavirus M protein that shows excellent efficacy in Syrian golden hamster models—binds to and stabilizes the M protein dimer in an altered conformational state between its long and short forms, preventing the release of infectious virus.
