Engineering a genomically recoded organism with one stop codon

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08501-xOchre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into proteins.

Feb 5, 2025 - 20:35
 0
Engineering a genomically recoded organism with one stop codon

Nature, Published online: 05 February 2025; doi:10.1038/s41586-024-08501-xOchre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into proteins.