Bacterial reverse transcriptase synthesizes long poly(A)-rich cDNA for antiphage defense | Science

Prokaryotic defense-associated reverse transcriptases (DRTs) were recently identified with antiviral functions; however, their functional mechanisms remain largely unexplored. Here we show that DRT9 forms a hexameric complex with its upstream noncoding ...

Jun 19, 2025 - 19:18
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Bacterial reverse transcriptase synthesizes long poly(A)-rich cDNA for antiphage defense | Science
Prokaryotic defense-associated reverse transcriptases (DRTs) were recently identified with antiviral functions; however, their functional mechanisms remain largely unexplored. Here we show that DRT9 forms a hexameric complex with its upstream noncoding ...