A man let snakes bite him for years. He could be the key to a universal antivenom

What's it like to get bit by a venomous snake? "It's like a bee sting times a thousand," Tim Friede says. Tim would know. Over the past few decades, he's let himself be bitten over 200 times by all kinds of venomous snakes — black mambas, taipans, cobras, kraits and more. With time, he's gradually built immunity to multiple types of venom. Could scientists help him share that immunity with others? Science reporter Ari Daniel joins Short Wave to explain how antivenom works, what scientists discovered and where the research may lead. Plus, what does Tim Friede have in common with Princess Bride?Want to hear about more medical discoveries? Email us at shortwave@nprg.org to tell us what areas of science you'd be interested in.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.

May 21, 2025 - 08:22
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A man let snakes bite him for years. He could be the key to a universal antivenom
The Egyptian cobra (<em>Naja haje</em>) is a lethal venomous snake native to Africa. Its bite is one of multiple that could be treated with a new universal antivenom... developed from a human named Tim Friede.

What's it like to get bit by a venomous snake? "It's like a bee sting times a thousand," Tim Friede says. Tim would know. Over the past few decades, he's let himself be bitten over 200 times by all kinds of venomous snakes — black mambas, taipans, cobras, kraits and more. With time, he's gradually built immunity to multiple types of venom. Could scientists help him share that immunity with others?

Science reporter Ari Daniel joins Short Wave to explain how antivenom works, what scientists discovered and where the research may lead. Plus, what does Tim Friede have in common with Princess Bride?

Want to hear about more medical discoveries? Email us at
shortwave@nprg.org to tell us what areas of science you'd be interested in.

Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at
plus.npr.org/shortwave.

(Image credit: Michele D'Amico)