The neurons that mediate a psychedelic’s long-term antidepressive effects
Nature, Published online: 02 April 2025; doi:10.1038/d41586-025-00979-3Psilocybin, a classic psychedelic, has therapeutic potential for psychiatric disorders. A specific brain circuit and receptor have now been found to be required for psilocybin’s long-term effects on neural plasticity and depression-related behaviour.

Nature, Published online: 02 April 2025; doi:10.1038/d41586-025-00979-3Psilocybin, a classic psychedelic, has therapeutic potential for psychiatric disorders. A specific brain circuit and receptor have now been found to be required for psilocybin’s long-term effects on neural plasticity and depression-related behaviour.