Cutting to survive: How cells remove DNA bridges at the last moment

If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic instability and cancer. Researchers at UNIST and IBS have experimentally revealed for the first time how a critical protein acts as a last resort to eliminate these dangerous DNA bridges, often cutting it close during the final moments of cell division.

May 19, 2025 - 16:22
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If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic instability and cancer. Researchers at UNIST and IBS have experimentally revealed for the first time how a critical protein acts as a last resort to eliminate these dangerous DNA bridges, often cutting it close during the final moments of cell division.