Bat genomes illuminate adaptations to viral tolerance and disease resistance

Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08471-0A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene ISG15 that aid disease resistance in bats, including to coronaviruses.

Feb 2, 2025 - 11:50
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Bat genomes illuminate adaptations to viral tolerance and disease resistance

Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08471-0A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene ISG15 that aid disease resistance in bats, including to coronaviruses.