A polyene macrolide targeting phospholipids in the fungal cell membrane

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08678-9Mandimycin, a polyene macrolide, exhibits strong antifungal activity and possesses a mode of action that is distinct from other compounds of this class.

Mar 19, 2025 - 17:45
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A polyene macrolide targeting phospholipids in the fungal cell membrane

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08678-9Mandimycin, a polyene macrolide, exhibits strong antifungal activity and possesses a mode of action that is distinct from other compounds of this class.